Figure 1: An artist’s impression of endogenous and exogenous antigen uptake and presentation. The section on the left displays antigens broken down and display to MHCI/TCR/CD8+ pathway while the right side shows antigens endocytosed and presented to MHCII/TCR/CD4+ pathway. In the middle lies a key pathway called cross-presentation which takes antigens from MHCII to MHCI display which is a robust mechanism for presenting tumour antigens as well.