Characteristic

COPD patients

Healthy controls

p value

Subjects

21

14

 

Pre vaccination sample (T0)

7

10

 

Ages (years; mean[range])

66(38-80)

54(36-86)

0.01#

Gender (M/F)

14/7

8/6

0.57&

Body Mass Index (mean[range])

26(13-33)

27(21-32)

0.80#

Previous vaccination

76%  (16/5)

79%  (11/3)

0.35&

Co-morbidity*

29%  (6/15)

14%  (2/12)

0.18&

Smoking history (current or past)

100% (21/0)

29% (4/10)

< 0.001&

Inhaled steroids

66% (14/7)

-

-

* Presence of hypertension, hyperlipidemia, diabetes or cardiovascular disease
# Unpaired t test
& Chi squared test

Table 1: Demographic and clinical characteristics.