| Strain |
Florfenicol |
floR |
hilA |
sopB |
pnp |
|
|
Log2 change (SEM†) |
Log2 change (SEM†) |
Log2 change (SEM†) |
Log2 change (SEM†) |
| 745 |
1 µg/ml |
5.21 |
(0.13)*** |
0.23 |
(-0.08) |
0.15 |
(0.07) |
0.50 |
(0.13) |
|
5 µg/ml |
5.50 |
(0.14)*** |
0.11 |
(0.10) |
0.26 |
(0.08) |
1.36 |
(0.21)* |
|
30 µg/ml |
5.07 |
(0.09)*** |
-0.19 |
(0.06) |
-0.41 |
(0.08) |
1.94 |
(0.15)** |
|
|
|
|
|
|
|
|
|
|
| 530 |
1 µg/ml |
5.67 |
(0.21)*** |
-0.03 |
(0.12) |
-0.30 |
(0.18) |
0.42 |
(0.09) |
|
5 µg/ml |
5.25 |
(0.19)*** |
-0.68 |
(0.15) |
-0.64 |
(0.19) |
1.40 |
(0.18)* |
|
30 µg/ml |
4.82 |
(0.12)*** |
-1.05 |
(0.13)* |
-1.49 |
(0.21)* |
1.65 |
(0.14)** |
|
|
|
|
|
|
|
|
|
|
| 19823 |
1 µg/ml |
5.03 |
(0.21)*** |
-0.19 |
(0.10) |
0.37 |
(0.13) |
0.76 |
(0.06)** |
|
5 µg/ml |
5.50 |
(0.11)*** |
-0.47 |
(0.08) |
-0.13 |
(0.08) |
1.64 |
(0.09)*** |
|
30 µg/ml |
4.71 |
(0.06)*** |
-0.62 |
(0.07)* |
-0.07 |
(0.11) |
1.54 |
(0.06)*** |
|
|
|
|
|
|
|
|
|
|
| 745ΔfloR |
1 µg/ml |
N/A |
|
0.18 |
(0.10) |
0.04 |
(0.09) |
0.53 |
(0.11) |
|
5 µg/ml |
N/A |
|
-0.22 |
(0.11) |
-0.49 |
(0.15) |
1.10 |
(0.09)** |
|
30 µg/ml |
N/A |
|
-0.78 |
(0.07)** |
-0.75 |
(0.10)* |
1.35 |
(0.06)*** |
|
| †Standard Error of the Mean; * P < 0.05; ** P < 0.01; *** P < 0.001 |
| Table 2: Gene expression differences in S. Typhimurium DT104 after exposure to florfenicol relative to control cultures without florfenicol. |
