Figure 4: Changes in canine OSA D17 viability after incubation with CM from WJMSC loaded with DOX-M. + indicates a significant difference between the test variable compared to the control population with a p-value = 0.05. Significant differences were found when comparing the 10 ÁM free DOX at 72 hours to the control OSA population (p=0.0506). Significant differences were also observed between the control OSA population and the 10 ÁM free DOX, the 10 ÁM DOX-M, and the 1 ÁM DOX-M at 96 hours (p=0.002, 0.0037, and 0.0222 respectively).