Case Age (months) Sex Municipality Micro Macro Nested PCR* qPCR 0014 >24 No data Planeta Rica No significant lesions No data - - 0105 60 Female La Ceja Perivascular cuffing Bruxism, ptyalism - - 0151 30 Male Tulua Inclusion bodies Blind, recumbency - - 0212 24 Male Monteria Non suppurative meningoencephalitis Recumbency, opisthotonos Positive BoHV-5 Positive BoHV-5 0303 48 Male Valledupar No data Hyperexcitability, no menace reflex - - 0310 6 Male Bucaramanga Meningitis Ptyalism, bruxism, circling Positive BoHV-5 - 0324 8 Male Valledupar Congestion, hemorrhage Found dead Positive BoHV-5 - 0413 19 Female Palmira Meningitis and congestion circling, recumbency - - 0669 >24 No data Monteria Edema, congestion No data - - 0853 >24 No data Tierra Alta Perivascular cuffing, gliosis No data - - 0854 >24 No data Cienaga de Oro Gliosis, edema, congestion, perivascular cuffing No data - - 0878 18 Male Valledupar Perivascular cuffing Recumbency, opisthotonos Positive BoHV-5 - 0904 23 Female La Dorada Meningitis Blind, circling, recumbency - - 0945 >24 No data Puerto Libertador Edema, congestion, hemorrhage No data - - 0949 >24 No data Montelibano Edema. No data - - 1014 9 Female Sincelejo Perivascular cuffing Ptyalism, bruxism, recumbency Positive BoHV-5 Positive BoHV-5 1029 51 Female Puerto Tejada Meningitis Found dead - - 1044 42 Male Valledupar Non suppurative meningoencephalitis circling, recumbency, opisthotonos - - 1697 >24 No data Monteria Gliosis, edema, congestion, malacia No data - - 1824 >24 No data Monteria Gliosis, edema, satellitosis No data - - 0454 >24 No data No data Edema, gitter cells, congestion, perivascular cuffing No data - - * Pedraza et al. [28].

Table 1: Major clinicopathological findings in cattle affected with nonspecific encephalitis identified as BoHV-5 positive by qPCR.