LPS |
Control |
101 ( cfu) |
103 ( cfu) |
105 ( cfu) |
107 ( cfu) |
109 ( cfu) |
Ruffled fur |
0.0 ± 0.055f |
0.48 ± 0.055e |
1.02 ± 0.055d |
1.5 ± 0.055c |
2.14 ± 0.055b |
2.5 ± 0.055a |
Ocular discharges |
0.0 ± 0.044e |
0.0 ± 0.044e |
0.22 ± 0.044d |
0.56 ± 0.044c |
1.12 ± 0.044b |
1.68 ± 0.044a |
Level of alertness |
0.0 ± 0.04f |
0.78 ± 0.04e |
1.46 ± 0.04d |
1.84 ± 0.04c |
2.46 ± 0.04b |
2.72 ± 0.04a |
Laboured breathing |
0.0 ± 0.032f |
0.56 ± 0.032e |
0.78 ± 0.032d |
1.3 ± 0.032c |
1.8 ± 0.032b |
2.4 ± 0.032a |
|
Values with different superscript in a row are significantly different (P<0.05); LPS: LPS of Pasteurella multocida type B: 2; cfu: Colony Forming Unit. |
Table 2: Modifications in clinical signs in mice following oral inoculation of graded doses of LPS after 120 hours of inoculation. |