LPS Parameters Control 101 ( cfu) 103 ( cfu) 105 ( cfu) 107 ( cfu) 109 ( cfu) RBC (1012/L) 9.32 ± 0.036a 8.57 ± 0.036b 8.37 ± 0.036c 8.12 ± 0.036d 7.89 ± 0.036e 7.69 ± 0.036f Hemoglobin(g/L) 155.62 ± 0.233a 142.44 ± 0.233b 136.96 ± 0.233c 132.16 ± 0.233d 129.14 ± 0.233e 125.48 ± 0.233f PCV (L/L) 0.46 ± 0.0043a 0.398 ± 0.0043b 0.384 ± 0.0043b 0.352 ± 0.0043c 0.312 ± 0.0043d 0.282 ± 0.0043e WBC (×109/L) 7.72 ± 0.031a 4.92 ± 0.031b 3.90 ± 0.031c 2.94 ± 0.031d 2.20 ± 0.031e 1.92 ± 0.031f BNeutrophil(×109/L) 0.15 ± 0.0058f 0.213 ± 0.0058e 0.319 ± 0.0058d 0.423 ± 0.0058c 0.525 ± 0.0058b 0.621 ± 0.0058a SNeutrophil(×109/L) 19.06 ± 0.44f 41.22 ± 0.44e 54.30 ± 0.44d 61.66 ± 0.44c 76.20 ± 0.44b 84.24 ± 0.44a Lympho(×109/L) 5.580 ± 0.0186a 3.974 ± 0.0186b 3.148 ± 0.0186c 2.330 ± 0.0186d 1.920 ± 0.0186e 0.92 ± 0.0186f Monocytes (×109/L) 0.530 ± 0.0066a 0.430 ± 0.0066b 0.382 ± 0.0066c 0.30 ± 0.0066d 0.220 ± 0.0066e 0.130 ± 0.0066f Eosinophils(×109/L) 0.326 ± 0.0068f 0.38 ± 0.0068e 0.47 ± 0.0068d 0.60 ± 0.0068c 0.72 ± 0.0068b 0.83 ± 0.0068a Plasma Protein (g/L) 62.72 ± 0.467f 68.58 ± 0.467e 70.72 ± 0.467d 77.54 ± 0.467c 84.14 ± 0.467b 95.66 ± 0.467a PT (seconds) 26.50 ± 0.278f 41.90 ± 0.278e 49.66 ± 0.278d 58.96 ± 0.278c 67.10 ± 0.278b 75.70 ± 0.278a APTT (seconds) 53.30 ± 0.451f 67.94 ± 0.451e 76.56 ± 0.451d 88.20 ± 0.451c 103.60 ± 0.451b 117.54 ± 0.451a Thrombo(×109/L) 407.54 ± 1.097f 583.22 ± 1.097e 691.58 ± 1.097d 763.42 ± 1.097c 871.22 ± 1.097b 917.60 ± 1.097a

Values with different superscript in a row are significantly different (P<0.05); LPS: Lipopolysaccharide; PCV: Packed Cell Volume; WBC: White Blood Cells; BNeutrophils: Band Neutrophils; SNeutrophils: Segmented neutrophils; Lympho: Lymphocytes; PT: Prothrombin Time; APTT: Activated Partial Thromboplastin Time; Thrombo: Thrombocytes; cfu: Colony Forming Unit.

Table 4: Modifications in hematological parameters in mice following oral inoculation of graded doses of LPS after 120 hours of inoculation.