Group
Time intervals
SOD
*
GPX
*
Catalase
*
MDA
*
(U/gHb )
(U/gHb )
( U/gHb)
( Umol/L)
2
1383.7 ±115.4
244.8 ±9.7
1768.2 ±210.6
0.95 ±0.03
Group I
5
1275.0 ±24.4
213.1 ±11.9
1965.2 ±153.5
1.09 ±0.01
(Control)
8
1182.5 ±45.3
230.3 ±11.4
1817.5 ±161.6
1.03 ±0.06
11
1337.5 ±93.0
244.9 ±12.3
1825.5 ±221.7
1.00 ±0.03
17
1206.2 ±37.1
234.5 ±8.7
1778.7 ±169.3
0.86 ±0.08
2
1297.5 ±94.0
186.9 ±14.5
1655.0 ±188.2
1.08 ±0.04
Group II
5
1145.0 ±49.8
179.6 ±8.1
1839.2 ±154.9
1.14 ±0.04
(1 mg/kg)
8
1136.2 ±49.9
173.3 ±9.6
1708.0 ±141.6
1.09 ±0.03
11
1100.0 ±29.4
164.7 ±12.7
1690.2 ±199.2
1.10 ±0.03
17
1137.5 ±44.5
162.4 ±12.5
1638.0 ±167.6
1.09 ±0.04
Group III
(2 mg/kg)
2
1052.0 ±30.1
158.1 ±14.5
1539.5 ±169.2
1.11 ±0.02
5
1000.0 ±43.8
134.6 ±10.3
1699.0 ±151.3
1.13 ±0.00
8
986.2 ±36.4
132.1 ±11.4
1625.7 ±146.1
1.14 ±0.02
11
1033.7 ±31.3
145.1 ±8.3
1614.5 ±167.4
1.12 ±0.02
17
987.5 ±46.2
129.7 ±9.7
1531.7 ±174.5
1.18 ±0.01
2
800.0 ±12.4
119.7 ±7.1
1469.2 ±176.3
1.30 ±0.04
Group IV
5
828.7 ±67.7
132.6 ±10.0
1334.7 ±171.8
1.26 ±0.07
(3 mg/kg)
8
798.7 ±25.4
126.1 ±9.6
1598.7 ±147.9
1.19 ±0.05
11
815.0 ±57.8
131.1 ±8.2
1513.5 ±127.1
1.24 ±0.05
17
780.0 ±29.2
118.4 ±6.1
1533.5 ±186.8
1.26 ±0.02
2
738.7 ±28.4
115.8 ±7.1
1435.5 ±159.8
1.34 ±0.05
Group V
5
696.2 ±44.4
113.9 ±5.3
1468.0 ±112.0
1.31 ±0.02
(4 mg/kg)
8
686.2 ±18.2
126.7 ±5.1
1431.2 ±119.7
1.33 ±0.04
11
685.0 ±35.2
113.4 ±4.3
1378.2 ±179.8
1.31 ±0.02
17
693.7 ±38.5
116.6 ±6.2
1330.7 ±159.2
1.31 ±0.01
Table 1:
Blood SOD, GPX, Catalase and MDA after oral administration of various doses of salinomycin in sheep. *Significant difference between control and other groups at P<0.05
