SNP rs-number Chromosome position§ Gene feature genotype gene model m RNA position§ Allele change§ Protein position§ Residue change§ rs438480308 2:107117145 exon 4 CC missense 338 CTG ⇒ ATG 89 L [Leu] ⇒ M [Met] g.107117166A>G 2:107117166 exon 4 GG, AG missense 359 GCC ⇒ ACC 96 A [Ala] ⇒ T [Thr]  rs458688926 2:107117167 exon 4 CC, CG missense 360 GCC ⇒ GGC 96 A [Ala] ⇒ G [Gly] rs478409125 2:107117180 exon 4 CC cds-synon 373 GGC ⇒ GGG 100 G [Gly] ⇒ G [Gly] rs440590557 2:107117280 intron 4 CC N.Dǂ 18 C/A   not found rs460647173 2:107117291 intron 4 GG N.D. 29 G/C   not found rs717758716 2:107117300 intron 4 GG N.D. 38 G/T   not found rs480706808 2:107117321 Intron 4 AA N.D. 59 A/T   not found rs449522039 2:107117326 intron 4 AA, AT N.D. 63 A/T   not found rs469205385 2:107117328 intron 4 GG N.D. 66 G/T   not found g.107117369C>T 2:107117369 intron 4 TT, TC N.D. 107 T/C   not found rs520905988 2:107117380 intron 4 GG N.D. 118 A/G   not found rs482869550 2:107117389 Intron 4 AA N.D. 127 A/C   not found rs445253274 2:107117391 intron 4 GG N.D. 129 G/T   not found rs465479809 2:107117392 intron 4 GG N.D. 130 G/T   not found rs433744578 2:107117395 intron 4 GG N.D. 133 G/T   not found rs453907967 2:107117397 intron 4 GG N.D. 135 G/T   not found rs524557355 2:107117405 intron 4 CC N.D. 143 C/T   not found

Table 1: Influence of genetic variants on bovine tuberculosis susceptibility in Holstein cattle. The single-nucleotide polymorphisms (SNP) are located in the exon 4 and intron 4 of bovine SLC11A1 gene. ǂN.D.= not determined. §source: National Center for Biotechnology Information (NCBI), Database of Single Nucleotide Polymorphisms (dbSNP).