| Antigen |
Remarks |
Reference |
| Johnin PPD or PPDj |
Low specificity to diagnose
MAP over non-MAP mycobacterial exposure |
[71] |
| PPE family proteins (Map 41 and Map39) |
PPE proteins have high specificity to MAP. PPE do not cross-react with M. avium subsp. avium, |
[47] |
| PPE proteinsof MAP |
Elicits T cell based IFN-γ immunity in mice. |
[72] |
| Mycobacterial heat-shock protein of 70 kDa (HSP70) |
HSP 70 is well-defined antigen in comparison with PPD antigens and can be used to monitor CMI responses |
[73] |
| Recombinant HSP-65 and 35kda |
Early detection of CMI in the MAP infected calve |
[74] |
| L5P, Para-LP-01 and PstA |
Reported to be absent in MAA, but their diagnostic values remain to be validated |
[75,76] |
| Fusion protein ESAT-6 : CFP-10 |
Fusion protein differentiation of tuberculosis from MAP. Fusion protein is specific for tuberculosis |
[77] |
