| 
      
        | Parameter | Control/ Treated | Day    0 | Day    30 | Day    60 | Day    90 | Day    120 | Day    150 |  
        | Body weight (kg) | Control | 28.49 ± 1.48 | 28.59 ± 1.60 | 27.66 ± 1.78 | 28.76 ± 1.35 | 28.14 ± 1.49 | 28.39 ± 1.31 |  
        | Treated | 24.20 ± 2.05 | 24.24 ± 2.28 | 24.86 ± 1.95 | 24.91± 1.81 | 23.99 ± 2.28 | 23.90 ± 2.71 |  
        | Heart beat    (Beats/ min) | Control | 121.6 ± 10.48 | 114.8 ± 5.20 | 122.4 ± 6.76 | 131.6 ± 6.58 | 122.4 ± 4.66 | 122.4 ± 6.88 |  
        | Treated | 131.2 ± 11.27 | 126.4 ± 7.86 | 128.8 ± 7.94 | 130.4 ± 3.25 | 125.0 ± 5.51 | 139.0 ± 10.75 |  
        | Body temperature    (°F) | Control | 101.76 ± 0.36 | 101.10 ± 0.18 | 101.44 ± 0.29 | 101.14 ± 0.16 | 101.40 ± 0.33 | 101.14 ± 0.15 |  
        | Treated | 101.12 ± 0.45 | 101.5 ± 0.23 | 100.92 ± 0.20 | 101.06 ± 0.30 | 101.68 ± 0.23 | 101.63 ± 0.38 |  |