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Figure 3: Effect of EA on hindlimb suppression. (A) Gene expression as related to hindlimb suppression and EA effect. Realtimequantitative PCR analysis of expression for Mstn , MuRF-1, and MAFbx genes in WT,HS, and EA/HS mice. Relative transcript levels are shown (means ± SD). (B) Changes in myofibre diameters after EA. The effect of EA on prevention of muscle atrophy was10 shown by changes in myofibre diameters in three groups. Open circle, WT mice; closed squares, HS mice; open squares, EA/HS mice. *P < 0.05; **P < 0.01; ***P < 0.005. |