| Test (A) (Units) | 
        0 hours  | 
         | 
        2 hours  | 
         | 
        4 hours  | 
         | 
        8 hours  | 
         | 
        24 hours  | 
        P- | 
        Signi- | 
        Normal | 
       
      
        | 8 Placebos  | 
        Mean  | 
        SEM | 
        Mean  | 
        SEM | 
        Mean  | 
        SEM | 
        Mean  | 
        SEM | 
        Mean  | 
        SEM | 
        values | 
        ficance | 
        Range | 
       
      
        | Sodium (mmol/L) | 
        139.9  | 
        0.4867  | 
        139.1  | 
        0.613  | 
        139.75  | 
        0.6296  | 
        140.5  | 
        0.5337  | 
        139.133  | 
        0.4125  | 
        0.3352  | 
        N.S. | 
        136-146 | 
       
      
        | Potassium (mmol/L) | 
        4.31  | 
        0.073  | 
        4.456  | 
        0.1082  | 
        4.502  | 
        0.1278  | 
        4.4736  | 
        0.1153  | 
        4.348  | 
        0.1057  | 
        0.658  | 
        N.S. | 
        3.5-5.3 | 
       
      
        | Chloride (mmol/L) | 
        105.1667  | 
        0.7196  | 
        104.7  | 
        1.162  | 
        105.2  | 
        0.9153  | 
        104.2  | 
        1.23  | 
        104.83  | 
        0.958  | 
        0.9569  | 
        N.S. | 
        98-106 | 
       
      
        | CO2    (mmol/L) | 
        29.72  | 
        0.6545  | 
        29.51667  | 
        0.3834  | 
        29.1667  | 
        0.4761  | 
        30.62  | 
        0.2194  | 
        29.267  | 
        0.2827  | 
        0.1375  | 
        N.S. | 
        22-31 | 
       
      
        | Urea Nitrogen    (mg/dL) | 
        12  | 
        0.5887  | 
        11.714  | 
        0.6619  | 
        12.4  | 
        0.6734  | 
        12.6  | 
        0.8272  | 
        12.83  | 
        0.8234  | 
        0.8145  | 
        N.S. | 
        4.0-15.0 | 
       
      
        | Creatinine (mg/dL) | 
        1.0133  | 
        0.05058  | 
        1.027  | 
        0.05474  | 
        1.02  | 
        0.05629  | 
        1.1071  | 
        0.07051  | 
        1.02  | 
        0.05089  | 
        0.7559  | 
        N.S. | 
        0.5-1.4 | 
       
      
        | EGFR (mL/min) | 
        91.6  | 
        5.293  | 
        91.07  | 
        6.119  | 
        91.733  | 
        5.571  | 
        84.43  | 
        5.229  | 
        90  | 
        5.169  | 
        0.8697  | 
        N.S. | 
        100-125 | 
       
      
        | Glucose (mg/dL) | 
        106.5  | 
        2.83  | 
        102.5  | 
        4.247  | 
        99.067  | 
        3.399  | 
        99.286  | 
        2.858  | 
        102.2  | 
        3.76  | 
        0.5542  | 
        N.S. | 
        70-110 | 
       
      
        | Alkaline Phosp.    (U/L) | 
        71.8  | 
        5  | 
        72.73  | 
        5.794  | 
        74.214  | 
        5.791  | 
        74.71  | 
        5.311  | 
        74.2  | 
        5.577  | 
        0.9956  | 
        N.S. | 
        33-94 | 
       
      
        | ALT/WLA (U/L) | 
        23.063  | 
        2.22  | 
        23.73  | 
        2.576  | 
        24.231  | 
        2.727  | 
        24.5  | 
        2.851  | 
        24.6  | 
        2.675  | 
        0.9935  | 
        N.S | 
        7.0-45 | 
       
      
        | Bilirubin (mg/dL) | 
        0.7  | 
        0.05422  | 
        0.7  | 
        0.04364  | 
        0.66  | 
        0.04338  | 
        0.543**  | 
        0.04389  | 
        0.74  | 
        0.0466  | 
        0.0061  | 
        ** | 
        0.2-1 | 
       
      
        | RBC (M/uL) | 
        4.729  | 
        0.1053  | 
        5.381  | 
        0.6775  | 
        4.717  | 
        0.102  | 
        4.7047  | 
        0.107  | 
        4.789  | 
        0.1159  | 
        0.5068  | 
        N.S. | 
        4.4-5.9 | 
       
      
        | Hemoglobin (g/dL) | 
        13.91  | 
        0.2053  | 
        13.694  | 
        0.2014  | 
        13.727  | 
        0.2141  | 
        13.75  | 
        0.1952  | 
        13.933  | 
        0.1681  | 
        0.8683  | 
        N.S. | 
        13.3-17.7 | 
       
      
        | Hematocrit (%) | 
        40.86  | 
        0.5364  | 
        40.456  | 
        0.5837  | 
        40.633  | 
        0.517  | 
        40.767  | 
        0.5444  | 
        41.407  | 
        0.5871  | 
        0.7937  | 
        N.S. | 
        39-52 | 
       
      
      
        | MCV (fL) | 
        86.65  | 
        1.382  | 
        86.653  | 
        1.402  | 
        86.393  | 
        1.395  | 
        86.953  | 
        1.35  | 
        86.8  | 
        1.372  | 
        0.999  | 
        N.S. | 
        80-99 | 
       
      
        | MCH (pg) | 
        29.573  | 
        0.6049  | 
        29.329  | 
        0.5988  | 
        29.29333  | 
        0.5992  | 
        29.393  | 
        0.5926  | 
        29.253  | 
        0.592  | 
        0.9962  | 
        N.S. | 
        27-34 | 
       
      
        | MCHC (g/dL) | 
        33.95  | 
        0.2145  | 
        33.836  | 
        0.1869  | 
        33.76  | 
        0.2147  | 
        33.76  | 
        0.1802  | 
        33.6875  | 
        0.2404  | 
        0.921  | 
        N.S. | 
        32-36 | 
       
      
        | RDA (%) | 
        14.114  | 
        0.2307  | 
        14.08571  | 
        0.2424  | 
        14.16  | 
        0.2638  | 
        14.12  | 
        0.2213  | 
        14.153  | 
        0.2286  | 
        0.9995  | 
        N.S. | 
        12.0-15.0 | 
       
      
        | PLT (k/uL) | 
        227.3571  | 
        27.696  | 
        257.8  | 
        13.592  | 
        260.93  | 
        13.055  | 
        265.27  | 
        15.019  | 
        268.29  | 
        16.674  | 
        0.5081  | 
        N.S. | 
        150-440 | 
       
      
        | WBC (k/uL) | 
        6.2067  | 
        0.403  | 
        6.4438  | 
        0.4899  | 
        6.42  | 
        0.3721  | 
        6.48  | 
        0.3478  | 
        6.5933  | 
        0.4366  | 
        0.9763  | 
        N.S. | 
        4.5-11 | 
       
      
        | LYMP%-A (%) | 
        25.727  | 
        2.045  | 
        25.887  | 
        1.897  | 
        28.32  | 
        2.057  | 
        30.033  | 
        2.425  | 
        25.973  | 
        2.2211  | 
        0.5259  | 
        N.S | 
        20-40 | 
       
      
        | LYMP#-A (#/uL) | 
        1513.3  | 
        87.759  | 
        1566.7  | 
        90.326  | 
        1753.3  | 
        102.76  | 
        1906.7  | 
        149.75  | 
        1636.7  | 
        105.77  | 
        0.0947  | 
        N.S. | 
        600-4800 | 
       
      
        | Monocyte % (%) | 
        8.7667  | 
        0.463  | 
        8.12  | 
        0.4649  | 
        8.6733  | 
        0.5781  | 
        9.0933  | 
        0.2826  | 
        8.9667  | 
        0.3994  | 
        0.5927  | 
        N.S. | 
        2.0-10. | 
       
      
        | Monocyte # (#/uL) | 
        514.29  | 
        31.797  | 
        493.33  | 
        38.379  | 
        560  | 
        40  | 
        578.57  | 
        35.342  | 
        580  | 
        40.473  | 
        0.3588  | 
        N.S. | 
        0-950 | 
       
      
        | PMN% (%) | 
        61.747  | 
        2.401  | 
        62.573  | 
        2.174  | 
        59.267  | 
        2.456  | 
        56.107  | 
        2.574  | 
        61.62  | 
        2.431  | 
        0.3231  | 
        N.S. | 
        41-85 | 
       
      
        | PMN# (#/uL) | 
        3926.7  | 
        385.88  | 
        4086.7  | 
        450.27  | 
        3860  | 
        354.27  | 
        3692.9  | 
        303.38  | 
        4146.7  | 
        403.77  | 
        0.9235  | 
        N.S. | 
        1100-7700 | 
       
      
        | Eosinophil % (%) | 
        3.22  | 
        0.6681  | 
        2.8933  | 
        0.6384  | 
        3.4769  | 
        0.6575  | 
        3.6923  | 
        0.6253  | 
        2.8733  | 
        0.4922  | 
        0.9117  | 
        N.S. | 
        1.0-6.0 | 
       
      
        | Eosinophil #    (#/ul) | 
        207.14  | 
        43.517  | 
        186.67  | 
        38.872  | 
        220  | 
        43.86  | 
        235.71  | 
        42.753  | 
        193.33  | 
        38.379  | 
        0.9212  | 
        N.S. | 
        0-500 | 
       
      
        | Basophil % (%) | 
        0.54  | 
        0.03491  | 
        0.5267  | 
        0.07268  | 
        0.5714  | 
        0.05107  | 
        0.607***  | 
        0.07193  | 
        0.5667  | 
        0.05745  | 
        0.0001  | 
        *** | 
        0-1 | 
       
      
        | Basophil # (#/ul) | 
        13.33  | 
        9.085  | 
        20  | 
        10.69  | 
        21.429  | 
        10.995  | 
        35.714  | 
        12.839  | 
        33.333  | 
        12.599  | 
        0.5963  | 
        N.S. | 
        0-200 | 
       
      
     
    **P<0.01;  ***p<0.001 (at 0 vs. at 8 hours) |