Test B (Units) 0 hours

2 hours   4 hours

8 hours

24 hours P- Signi- Normal
6placebo + 2 Cyclo-Z Mean SEM Mean SEM Mean SEM Mean SEM Mean SEM values ficance Range
Sodium (mmol/L)

139.1

0.3877

139

0.6181

139.2

0.6159

139.3

0.6817

139.78

0.5646

0.3456 N.S 136-146
Potassium (mmol/L)

4.215

0.1143

4.092

0.104

4.235

0.1004

4.231

0.09353

4.2873

0.09184

0.5129

N.S 3.5-5.3
Chloride (mmol/L)

102.75

0.25

101.8

0.3498

101

0.7236

101.7

0.6186

103.2

0.9293

0.1615

N.S. 98-106
CO2 (mmol/L)

30.83

0.679

29.96

0.3781

29.1667

0.4437

28.1**

0.5331

30.02

0.4505

0.0073

** 22-31
Urea Nitrogen (mg/dL)

14.25

1.388

13.2

0.3374

11.75

0.25

15.533

2.15

12.4

0.7797

0.0742

N.S. 4.0-15.0
Creatinine (mg/dL)

1.022

0.06742

0.991

0.05789

0.975

0.05789

0.9667

0.04942

0.9909

0.07384

0.825

N.S. 0.5-1.4
EGFR (mL/min)

96.78

9.175

98.73

7.966

100

7.967

97.44

5.144

101

12.449

0.6886

N.S. 100-125
Glucose (mg/dL)

97.56

9.175

96.45

7.966

95.2

7.967

95.778

5.144

94.818

12.449

0.7294

N.S. 70-110
Alkaline Phosp. (U/L)

72.25

5.10

80.9

6.033

91.111

6.308

91.78

7.447

82.82

10.441

0.0652

N.S. 33-94
ALT/WLA (U/L)

42.9

13.469

36.89

6.199

32.5

6.144

34.11

6.232

31.82

7.619

0.1214

N.S 7.0-45
Bilirubin (mg/dL)

0.756

0.07689

0.75

0.08925

0.578

0.0965

0.544*

0.0862

0.6545

0.0131

0.0411

*. 0.2-1
RBC (M/uL)

5.853

0.1202

5.627

0.1198

5.678

0.1102

5.626

0.1014

5.697

0.09829

0.0856

N.S. 4.4-5.9
Hemoglobin (g/dL)

13.78

0.2527

13.7

0.0528

13.722

0.1011

13.69

0.1372

13.691

0.266

0.0863

N.S. 13.3-17.7
Hematocrit (%)

40.45

0.4029

40.482

0.4193

40.422

0.2225

40.2

0.391

40.509

0.5677

0.0082

N.S. 39-52
MCV (fL)

84.93

1.195

85.445

1.219

87.1

1.25

86.567

1.163

85.109

1.303

0.9306

N.S. 80-99
MCH (pg)

28.733

0.5347

29.027

0.5172

29.533

0.5963

29.522

0.4924

28.791

0.5132

0.9509

N.S. 27-34
MCHC (g/dL)

33.68

0.1438

33.918

0.1074

33.95556

0.1981

34.0444

0.1543

33.782

0.09856

0.0468

* 32-36
RDW (%)

14.238

0.0738

14.1

0.2472

13.7556

0.1615

13.833*

0.1615

13.95

0.1355

0.0045

0.034 12.0-15.0
PLT (k/uL)

232.889

28.186

258

29.163

265.13

37.2

269.56

28.082

254.55

26.61

0.9998

N.S. 150-440
WBC (k/uL)

5.744

0.3258

5.8091

0.2614

5.822

0.3899

6.311

0.3247

5.8545

1.404

0.7898

N.S. 4.5-11
LYMP%-A (%)

29.422

0.5038

28.773

1.363

31.887

0.8981

30.533

1.571

29.745

0.9703

0.0936

N.S 20-40
LYMP#-A (#/uL)

1688.9

113.82

1640

130.34

1844.4

128.01

1811.1

126.81

1700

83.597

0.1563

N.S. 600-4800
Monocyte % (%)

10.411

0.2039

9.1818

0.5774

8.6778

0.7213

8.5889

0.7933

9.4455

0.7731

0.0401

N.S. 2.0-10.
Monocyte # (#/uL)

588.89

30.151

536.36

39.166

522.22

65.711

533.33

54.356

464.47

56.407

0.4749

N.S. 0-950
PMN% (%)

55.567

2.915

57.045

1.589

53.178

1.083

54.944

1.383

55.945

0.9473

0.0748

N.S. 41-85
PMN# (#/uL)

3062.5

145.19

3318.2

93.845

3100

151.51

3662.5*

164.28

3345.5

130.34

0.0114

* 1100-7700
Eosinophil % (%)

4.0778

0.7256

4.4545

0.6949

5.6889

0.6814

5.4222

0.7279

4.3909

0.6685

0.9905

N.S. 1.0-6.0
Eosinophil # (#/ul)

233.33

47.672

263.64

53.832

333.33

54.356

333.33

45.227

254.55

52.225

0.8746

N.S. 0-500
Basophil % (%)

0.522

0.5455

0.02611

0.578***

0.01306

0.5111

0.02132

0.4727

0.025

0.0002

*** 0-1
Basophil # (#/ul)

11.111

0

18.182

0

11.111

0

11.111

0

0

0

0

N.S. 0-200
*p<0.05; **p<0.01; ***p<0.001 ( At 0 hour vs. at 4 or 8 hours)
Table 2: Study Subjects who took 2 capsules of Cyclo-Z and 6 capsules of Placebos.