Test D (Units) 0 hours   2 hours   4 hours   8 hours   24 hours     P- Signifi- Normal
8 Cyclo-Z Mean SEM Mean SEM Mean SEM Mean SEM Mean SEM values cance Range
Sodium 139.5 0.4713 139.5 0.3793 139.08 0.5568 140.17 0.4508 139.92 0.4681 0.5107 N.S. 136-146
Potassium (mmol/L) 4.148 0.078 4.314 0.1209 4.3 0.1004 4.1758 0.0719 4.1091 0.0757 0.4322 N.S. 3.5-5.3
Chloride (mmol/L) 105.2 0.8001 103.4 0.9275 104.3 1.022 103.5 1.19 104.4 0.8124 0.688 N.S. 98-106
C02 (mmol/L) 29.46 0.6547 29.4 0.5874 27.96 1.142 28.8 1.523 29.36 0.7243 0.7977 N.S. 22-31
Urea Nitrogen (mg/dL) 13.4 1.208 12.6 1.632 13.8 1.157 14.6 1.208 12.2 0.9696 0.6807 N.S. 4.0-15.0
Creatinine (mg/dL) 0.925 0.06411 0.942 0.06207 0.917 0.07679 1.0333 0.08195 0.9333 0.0666 0.7451 N.S. 0.5-1.4
EGFR (mL/min) 103.3 6.051 101 6.279 107.83 9.036 92.17 5.875 102.7 6.634 0.5963 N.S. 100-125
Glucose (mg/dL) 107.6 5.912 91.67 6.261 92.583 2.832 88.333* 2.435 103.92 7.13 0.0495 * 70-110
Alkaline Phosp (U/L) 76 8.842 75.46 8.395 78.333 8.804 78.75 7.705 75.75 8.865 0.9978 N.S. 33-94
ALT/WLA (U/L) 34.667 4.978 33.54 4.848 34.417 5.129 35.17 5.11 35.58 5.479 0.9989 N.S. 7.0-45
Bilirubin (mg.dL) 0.842 0.0829 0.807 0.0759 0.718 0.0645 0.667 0.0753 0.8417 0.0583 0.342 N.S. 0.2-1
RBC (M/uL) 4.709 0.1155 4.688 0.1236 4.689 0.1184 4.6633 0.1156 4.665 0.1221 0.9987 N.S. 4.4-5.9
Hemoglobin (g/dL) 14.08 0.2826 14.1 0.2753 14.042 0.3103 13.93 0.2944 13.883 0.3005 0.9798 N.S. 13.3-17.7
Hematocrit (%) 41.442 0.7754 41.667 0.7188 41.383 0.7507 41.275 0.753 40.983 0.7868 0.9788 N.S. 39-52
Mean C Volume (fL) 83.56 5.17 88 1.354 88.285 1.318 89.009 1.616 88.317 1.435 0.5916 N.S. 80-99
MCH (pg) 30.127 0.7212 30.033 0.6379 30.09167 0.6578 29.975 0.656 29.942 0.6759 0.9996 N.S. 27-34
MCHC (g.dL) 34.045 0.281 33.858 0.2475 33.94167 0.2379 33.7417 0.1975 33.85 0.2512 0.9312 N.S. 32-36
Red Dist.Width (%) 13.885 0.3013 13.73333 0.329 13.8 0.3136 13.7167 0.2966 13.736 0.3304 0.9945 N.S. 12.0-15.0
Platelet (k/uL) 225.6923 13.542 229.3333 15.742 222.25 14.748 228.5 14.892 226.67 12.891 0.9974 N.S. 150-440
WBC (k/uL) 6.5583 0.6437 6.6333 0.7451 6.8545 0.6131 6.7545 0.59 6.4333 0.5699 0.9917 N.S. 4.5-11
Lymphocyte-A (%) 25.7 2.801 24.925 2.498 27.1 2.335 29.192 2.162 25.775 1.971 0.7356 N.S. 20-40
Lymphocyte-A (#/uL) 1553.8 160.77 1591.7 181.52 1783.3 194.95 2009.1 218.03 1625 167.03 0.4167 N.S. 600-4800
Monocyte (%) 8.8385 0.8329 8.0333 0.6242 8.5833 0.6911 8.5273 0.556 8.325 0.6901 0.9408 N.S. 2.0-10.
Monocyte (#/uL) 546.15 58.415 525 59.193 558.33 55.677 600 72.613 541.67 54.297 0.932 N.S. 0-950
PMN (%) 61.592 3.17 63.123 2.97 59.842 2.84 57.018 2.675 61.355 2.796 0.6598 N.S. 41-85
PMN (#/uL) 4084.6 605.93 4258.7 676.28 3984.6 469.3 3910 461.55 4025 493.45 0.9941 N.S. 1100-7700
Eosinophil (%) 3.6154 0.7501 3.5583 0.8083 3.9417 0.7941 4.2727 0.8117 3.7 0.8476 0.9715 N.S. 1.0-6.0
Eosinophil (#/uL) 215.4 55.287 209.09 63.896 250.04 64.536 281.82 61.523 233.33 56.855 0.9223 N.S. 0-500
Basophil (%) 0.4308 0.04585 0.4333 0.05195 0.5333 0.05271 0.4636 0.06778 0.55 0.0646 0.418 N.S. 0-1
Basophil (#/uL) 0 0 0 0 8.3333 8.333 9.0909 9.091 8.333 8.333 0.9999 N.S. 0-200
*p<0.05 (At O vs. at 8 hours)
Table 4: Study Subjects who took 8 capsules of Cyclo-Z.