Figure 3: Graph showing unaffected paired-pulse facilitation in Tg2576. In each hippocampal slice, facilitation was tested using pairs of stimuli at intervals ranging from 200 ms to 10 ms. While responses were smaller in Tg2576, the degree of facilitation, measured by the ratio of the response to the second stimulus compared to the first stimulus in each pair, was similar in Tg2576 compared to WT slices. The inset shows examples responses recorded using 50 ms interval paired pulses from a WT slice (left) and a Tg2576 slice (right). Scale bars represent 0.5 mV by 25 ms for both traces.