Figure 3: Interaction of DMET Genes with Compounds and Human Diseases. Cytoscape was applied to depict the relationship between DMET genes and compounds and human diseases. Only the top 5 chemicals and the top 5 diseases associated with the top 10 sex-biased DMET genes were analyzed; and more details can be found in Supplementary Table 1. The following symbols and colors are used: pink circles for genes, white diamond for chemicals, and red octagons for human diseases.