Period

Parameters

Control
X ± SD

ß-NOA 10 ppm
X ± SD

ß-NOA 20 ppm
X ± SD

SUBACUTE

AST (U/L)

113.5 ± 3.7

134.5 ± 12.3*

176.5 ± 17.6*

ALT (U/L)

56.1 ± 3.3

61.1 ± 5.2

62.2 ± 3.3*

LDH (U/L)

697.8 ± 9.5

908.7 ± 15.7*

989.4± 16.6*

TPRO (g/dL)

6.3 ± 0,2

6.5 ± 0.8

7.129 ± 0.8

TALB (mg/dL)

3.8 ± 0.07

4.3 ± 0.4*

4.0 ± 0.2

TKOL (mg/dL)

43.1 ± 3.2

43.5 ± 7.1

59.7 ± 6.4*

TBİL (mg/dL)

0.06 ± 0.011

0.08 ± 0.004*

0.08 ± 0.009*

 

 

 

 

 

SUBCHRONIC

 

 

AST (U/L)

98.0 ± 4.6

107.4 ± 4.1*

139.8 ± 1.9*

ALT (U/L)

45.2 ± 3.7

41.7 ± 4.8

33.5 ± 2.6*

LDH (U/L)

666.7 ± 9.6

880.8 ± 16.5*

904.2 ± 26.6*

TPRO (g/dL)

6.5 ± 0.6

6.7 ± 0.5

6.7 ± 0.7

TALB (mg/dL)

4.3 ± 0.2

3.8 ± 0.2*

3.7 ± 0.4*

TKOL (mg/dL)

44.1 ± 2.4

46.0 ± 5.8

52.1 ± 7.1*

TBİL (mg/dL)

0.05 ± 0.0004

0.07 ± 0.0007*

0.07 ± 0.006*

Each value represents the Mean ± SD. * p<0.05
Table 1: Effects of ß-NOA 10-20 ppm on serum biomarker levels of rats at subacute and subchronic.