Period

Parameters

Control
X ± SD

4-CPA 10 ppm
X ± SD

4-CPA 20 ppm
X ± SD

SUBACUTE

 

SOD U/ml

2144.6 ± 16.0

1780,2 ± 28.5*

2204.2 ± 20.5*

GR U/ml

1.8 ± 0,1

2.9 ± 0.3*

2.3 ± 0.2*

CAT U/ml

320.6 ± 18.5

216.5 ± 29.9*

241.6 ± 26.2*

GSH-Px U/ml

188.6 ± 3.7

150.2 ± 6.7*

160.6 ± 5.4*

GST U/ml

1.5 ± 0.07

0.7 ± 0.07*

0.7 ± 0.05*

G6PD U/ml

1.0 ± 0.03

0.6 ± 0.1*

0.8 ± 0.1*

GSH mg/ml

1.3 ± 0.02

1.2 ± 0.04

1.2 ± 0.02

MDA nmol/dl

1.6 ± 0.1

2.4 ± 0.1*

2.6 ± 0.3*

 

 

 

 

 

SUBCHRONIC

 

SOD U/ml

2181.7 ± 23.0

2132.9 ± 23.6*

2169.9 ± 26.3

GR U/ml

2.2 ± 0.1

1.3 ± 0.1*

0.7 ± 0.1*

CAT U/ml

320.6 ± 10.2

325.4 ± 8.0

305.1 ± 9.2

GSH-Px U/ml

205.0 ± 6.9

127.6 ± 5.1*

134.4 ± 6.9*

GST U/ml

1.6 ± 0.1

0.9 ± 0.09*

1.1 ± 0.2*

G6PD U/ml

1.3 ± 0.04

0.9 ± 0.3*

0.9 ± 0.09*

GSH mg/ml

1.7 ± 0.1

1.5 ± 0.1*

1.5 ± 0.1*

MDA nmol/dl

1.7 ± 0.3

3.0 ± 0.1*

3.2 ± 0.2*

Each value represents the Mean ± SD. * p<0.05
Table 4: Effects of 4-CPA 10-20 ppm on antioxidant defence systems and MDA contents in erythrocyte of rats at subacute and subchronic.