Period

Parameters

Control
X ± SD

4-CPA 10 ppm
X ± SD

4-CPA 20 ppm
X ± SD

SUBACUTE

 

SOD U/g

2191.4 ± 33.0

2131.3 ± 23,5*

2191.1 ± 32.2

GR U/g

0.9 ± 0.07

0.8 ± 0.08*

0.9 ± 0.07

CAT U/g

39.7 ± 6.5

13.0 ± 2.5*

12.8 ± 3.0*

GSH-Px U/g

65.9 ± 2.8

52.3 ± 4.0*

47,7 ± 2.9*

GST U/g

3.2 ± 0.1

4.4 ± 0.3*

3.5 ± 0.2*

G6PD U/g

0.3 ± 0.02

0.2 ± 0.03*

0.1 ± 0.03*

GSH mg/g

17.4 ± 0.7

17.3 ± 0.2

11.3 ± 1.3*

MDA nmol/g

2.0 ± 0.5

24.0 ± 1.2*

25.5 ± 1.1*

 

 

 

 

 

SUBCHRONIC

 

SOD U/g

2272.6 ± 20.6

2266.1 ± 5.1

2247.9 ± 16.8*

GR U/g

1.0 ± 0.05

0.3 ± 0.04*

0.2 ± 0.02*

CAT U/g

25.8 ± 2.3

24.8 ± 2.0

24.5 ± 3.7

GSH-Px U/g

107.2 ± 3.7

108.1 ± 3.6

93.0 ± 4.5*

GST U/g

3.4 ± 0.1

1.9 ± 0.6*

3.1 ± 0.7

G6PD U/g

0.3 ± 0.02

0.3 ± 0.03

0.3 ± 0.03

GSH mg/g

15.0 ± 1.0

7.5 ± 1.1*

3.2 ± 1.2*

MDA nmol/g

12.4 ± 1.8

18.9 ± 1.7*

23.6 ± 1.8*

Each value represents the Mean ± SD. * p<0.05
Table 6: Effects of 4-CPA 10-20 ppm on antioxidant defence systems and MDA contents in heart of rats at subacute and subchronic.