| 
      Each value represents the Mean ± SD. * p<0.05
        | Period | Parameters | ControlX ± SD
 | 4-CPA 10 ppmX ±    SD
 | 4-CPA 20 ppmX ±    SD
 |  
        | SUBACUTE   | SOD U/g | 2170.9 ±    17.0 | 2170.1 ±    13,5 | 2148.5 ±    15.2* |  
        | GR U/g | 2.0 ±    0.1 | 1.8 ±    0.08* | 1.5 ±    0.1* |  
        | CAT U/g | 191.5 ±    15.3 | 135.2 ±    17.1* | 70.7 ±    11.4* |  
        | GSH-Px U/g | 276.8 ±    9.6 | 200.9 ±    8.8* | 172.6 ±    9.7* |  
        | GST U/g  | 3.3 ±    0.2 | 3.1 ±    0.2 | 3.3 ±    0.1 |  
        | G6PD U/g  | 1.0 ±    0.08 | 1.1 ±    0.06* | 0.9 ±    0.08 |  
        | GSH mg/g | 4.8 ±    0.4 | 6.4 ±    0.6* | 3.5 ±    0.2* |  
        | MDA nmol/g  | 38.5 ±    0.6 | 44.2 ±    1.4* | 46.8 ±    3.8* |  
        |   |   |   |   |   |  
        | SUBCHRONIC   | SOD U/g | 2229.4 ±    15.5 | 2217.5 ±    18.4 | 2222.9 ±    16.9 |  
        | GR U/g | 2.4 ±    0.2 | 2.6 ±    0.4 | 2.5 ±    0.1 |  
        | CAT U/g | 189.0 ±    16.1 | 140.1 ±    8.0* | 153.5 ±    9.5* |  
        | GSH-Px U/g | 204.8 ±    7.7 | 178.0 ±    9.5* | 174.7 ±    8.5* |  
        | GST U/g  | 3.4 ±    0.2 | 3.1 ±    0.3 | 3.1 ±    0.2 |  
        | G6PD U/g  | 1.0±    0.04 | 1.1 ±    0.01* | 1.1 ±    0.02* |  
        | GSH mg/g | 4.5 ±    0.5 | 5.9 ±    0.4* | 6.3 ±    0.6* |  
        | MDA nmol/g  | 32.5 ± 0.8 | 49.4 ± 0.3* | 53.0 ± 2.4* |  |