Drug

2C8

2C9

2C19

3A4

Oxaprozine

NSAID

 

S

 

 

Leflunomide

DMARD

S, Inh

S, Inh

 

 

Metronidazol

Antibiotic agent

Inh

S, Inh

 

S, Inh

Amoxicilline

Antibiotic agent

 

 

S

 

Clindamycine

Antibiotic agent

 

 

 

S, Inh

Table 4: Potentially adverse side effects because of enzyme overload.