M1
M2
M3
Vm
Km
CYP 3A4
0.04 ± 0.006
40.1 ± 16.1
0.032 ± 0.003
10.5 ± 4.8
0.20 ± 0.02
57.5 ± 14.7
CYP 3A5
0.025 ± 0.003
10.1 ± 5.1
0.021 ± 0.002
1.5 ± 1.8
0.16 ± 0.01
14.5 ± 2.7