Analyte Mean ±SD Median (Range-Max – Min)

Diabetic CD1mice- Pre fasting

Diabetic CD1 mice- Post fasting

Diabetic db/db mice Pre fasting

Diabetic db/db mice Post fasting

Body weight-BW

24.02 ± 3.10 25.75 (25.30-24.20)

22.60 ± 2.60* 22.5 (24.50-21.90)

36.68 ± 4.10 36.90 (37.50-33.10)

35.43 ± 2.40 35.10 (36.50-34.30)

Total WBC (× 103/μL)

6.71 ± 1.31 (6.81) (8.21-5.15)

4.65 ± 1.03* 4.57 (5.97-3.46)

8.47 ± 2.11 8.18 11.88-6.04

6.87 ± 2.17 6.48 10.89-4.69

Lymphocytes-L (%)

71.32 ± 3.07 71.95 (74.50-66.40)

41.15 ± 10.37* 40.90 (52.70-32.20)

79.98 ± 3.66 81.10 83.70-73.10

72.59 ± 3.51* 72.00 77.00-68.20

Monocytes -M(%)

7.53 ± 1.38 (8.05) (8.80-5.70)

14.08 ± 3.78* (14.05) (17.40-10.80)

6.43 ± 1.42 6.25 8.90-5.00

6.41 ± 1.60 5.95 9.00-4.70

Granulocytes-G (%)

21.15 ± 2.30 21.20 (24.90-18.10)

44.78 ± 6.89* 45.00 (52.60-32.60)

13.60 ± 2.41 13.15 18.00-11.20)

21.00 ± 2.58* 21.55 23.60-16.60

RBC (× 106/μL)

6.97 ± 0.49 7.02 (7.52-6.23)

7.78 ± 0.28* 7.90 (7.94-7.35)

9.18 ± 0.50 9.11 (9.93-8.35)

8.67 ± 0.40* 8.79 (9.26-7.91)

MCV (fL)

59.33 ± 0.56 59.20 (60.10-58.70)

59.63 ± 0.56 59.60 (60.20-59.10)

58.20 ± 0.68 58.40 (59.00-57.10)

57.34 ± 0.53* 57.30 (58.10-56.40)

HCT (%)

41.33 ± 3.09 41.70 (45.00-36.50)

46.33 ± 1.91* 47.10 (47.60-43.50)

53.31 ± 3.33 52.65 (58.50-47.60)

49.66 ± 2.71* 50.30 53.80-44.60)

MCH (pg)

17.43 ± 0.22 17.45 (17.70-17.10)

17.95 ± 0.24 17.85 (18.30-17.80)

17.50 ± 0.34 17.40 (18.10-17.10)

17.46 ± 0.38 17.40 (18.00-17.00)

MCHC (g/dL)

29.43 ± 0.39 29.35 (30.10-29.10)

30.20 ± 0.62 29.95 (31.10-29.80)

30.13 ± 0.36 30.10 (30.80-29.70)

30.50 ± 0.63 30.40 (31.50-29.80)

RDW (%)

9.52 ± 0.10 9.50 (9.70-9.40)

10.28 ± 0.25* 10.40 (10.40-9.90)

9.78 ± 0.56 9.60 (10.80-9.30)

9.66 ± 0.45 9.50 (10.40-8.90)

Hemoglobulin-Hb(%)

12.18 ± 0.76 12.25 (13.1-11)

14.00 ± 0.64* 14.15 (14.6-13.1)

16.10 ± 0.98 16.1 (17.4-14.3)

15.18 ± 0.90 15.2 (16.5-13.5)

Platelets -PLT(× 103/μL)

1,097.00 ± 28.74 (1052) (1489-842)

1,183.00 ± 218.42 (1134) (1488-976)

646.75 ± 63.49 625 (779-577)

909.75 ± 69.03* 904 (995-833)

MPV (fL)

5.17 ± 0.23 5.15 (5.50-4.90)

5.53 ± 0.22* 5.50 (5.80-5.30)

5.48 ± 0.22 5.45 (5.80-5.10)

5.25 ± 0.20 5.30 (5.50-4.90)

Pct %

0.57 ± 0.12 0.55 (0.79-0.45)

0.65 ± 0.10 0.62 (0.80-0.57)

0.35 ± 0.02 0.35 (0.40-0.33)

0.47 ± 0.04* 0.48 (0.54-0.41)

PDW

8.58 ± 0.37 8.50 (9.10-8.20)

9.00 ± 0.32 9.05 (9.30-8.60)

8.15 ± 0.49 8.15 (8.90-7.40)

8.51 ± 0.53 8.55 (9.10-7.60)

Table 1: Haematology values in Pre and post fasting variables of STZ induced CD1 mice and db/db Presented as mean ± standard deviation (n=7) with median and range *p<0.05. * p<0.05 compared with pre and post fasted mice using unpaired student t test.