Day |
Treatment (mg/kg, p.o) |
SGOT (IU/L) M ± SEM |
SGPT (IU/L) M ± SEM |
ALP (U/l) M ± SEM |
Cholesterol (mg/dl) M ± SEM |
Triglyceride (mg/dl) M ± SEM |
Protein (gm/dl) M ± SEM |
HDL (mg/dl) M ± SEM |
LDL (mg/dl) M ± SEM |
Glucose (gm/dl) M ± SEM |
45 |
Vehicle control |
44.72 ± 2.66 |
42.21 ± 3.15 |
105.74 ± 4.34 |
119.70 ± 3.22 |
63.50 ± 3.70 |
7.60 ± 0.11 |
40.67 ± 2.86 |
76.33 ± 2.11 |
109.72 ± 5.30 |
Potassium Iodate (50) |
111.23 ± 2.69*** |
49.15 ± 4.46ns |
262.28 ± 4.21*** |
132.95 ± 5.25ns |
67.58 ± 3.10ns |
8.72 ± 0.41ns |
57.16 ± 3.76** |
62.27 ± 3.14** |
102.23 ± 4.28ns |
Potassium Iodate (85) |
137.93 ± 9.03*** |
56.89 ± 4.64ns |
397.02 ± 14.02*** |
153.76 ± 5.60*** |
123.85 ± 3.20*** |
7.63 ± 0.45ns |
44.45 ± 3.22ns |
85.71 ± 2.82ns |
98.34 ± 5.03ns |
Potassium Iodate (150) |
208.96 ± 12.45*** |
54.42 ± 4.11ns |
377.05 ± 14.33*** |
167.36 ± 5.12*** |
91.94 ± 3.33*** |
8.69 ± 0.23ns |
46.19 ± 2.12ns |
84.71 ± 3.56ns |
73.28 ± 4.95*** |
|
n=10. **P<0.01, ***P<0.001 and ns=not significant when compared to respective control group |
Table 7: Effect of daily oral administration of Potassium Iodate tablet up to 45 days on serum biochemical parameters of rat. |