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Figure 2: Ketamine-induced neurodegeneration in postnatal day 7 rats assessed by TUNEL labeling. Representative photographs indicate that TUNEL-positive cells are more numerous in layers II and III of the frontal cortex in the ketamine treated rat brain (B). Only a few TUNEL-positive cells were observed in the control (saline treated) rat brain (A). Scale bar = 60 μm. |