Time (min) CDRI-80/574 Concentration (μg) Ke/p Kb/p % Uptake
Blood Plasma RBC
1 1.37 ± 0.11 0.71 ± 0.11 0.51 ± 0.13 0.75 ± 0.31 0.89 ± 0.13 37.03 ± 8.92
2 1.24 ± 0.02 0.74 ± 0.16 0.34 ± 0.04 0.47 ± 0.07 0.76 ± 0.03 27.60 ± 2.97
3 1.24 ± 0.09 0.79 ± 0.06 0.27 ± 0.14 0.35 ± 0.21 0.71 ± 0.10 21.33 ± 11.12
10 1.36 ± 0.15 0.81 ± 0.11 0.37 ± 0.22 0.48 ± 0.33 0.77 ± 0.15 26.57 ± 13.59
12.5 1.24 ± 0.16 0.82 ± 0.06 0.25 ± 0.07 0.32 ± 0.12 0.69 ± 0.06 20.05 ± 6.29
15 1.42 ± 0.32 0.82 ± 0.09 0.41 ± 0.20 0.49 ± 0.20 0.78 ± 0.09 28.30 ± 8.34
20 1.26 ± 0.94 0.74 ± 0.04 0.34 ± 0.06 0.47 ± 0.11 0.77 ± 0.05 27.60 ± 4.81
30 1.29 ± 0.09 0.72 ± 0.03 0.41 ± 0.05 0.56 ± 0.05 0.80 ± 0.02 31.23 ± 1.79
Values are mean ± SD of three separate sets of experiment
Table 3: RBC partitioning of CDRI-80/574.