Fractions Degradation Constant (K) T1/2 (min)
S9 0.42 1.66
Microsomal 0.23 3.00
Cytosolic 0.027 25.72
Values are mean of three separate sets of experiment
Table 4: Metabolic Stability of CDRI-80/574 in S9, microsomal and cytosolic fractions.