Time (min)
CDRI 80-574 (% remaining)
Rat Hepatocytes
Human Hepatocytes
0
100
100
5
75
79
10
40
55
15
20
42
20
11
29
30
0
10
Values are mean of three independent sets of experiments
Table 5:
Metabolic Stability of CDRI-80/574 in Rat and Human Hepatocytes.