Spiked concentration of CDRI-80/574 (ng/ml) % of
CDRI-80/574 Epoxy metabolite
12.5 87.41 ± 3.15 91.23 ± 3.12
25 86 ± 4.14 81.43 ± 4.24
50 89.4 ± 4.05 83.23 ± 5.82
Values are mean ± SD of three separate sets of experiments
Table 8: Formation of epoxy metabolite from CDRI-80/574 in hepatic S9 of male Sprague Dawley rat.