Figure 1: Changes in F/f curves in the ICS inhalation-only (a) and in the LABA inhalation-only groups (b). There were no significant shifts in F/f curves from ICS1 to ICS4 compared with shams. However, F/f curves at LABA1 (##, p<0.01), LABA2 (##, p<0.01), and LABA4 (#, p<0.05) significantly shifted upward compared with sham animals. *p<0.05 compared with tensions of each frequency in shams.