Date Dose (mg/kg/d) C0 (ng/mL) C0/Dose
29/01 3.88 327.3 84.34
30/01 3.58 421.5 117.67
31/01 2.98 255.6 85.63
05/02 2.38 280.3 117.37
07/02 2.38 292.7 122.57
09/02 1.64 270.2 164.58
15/02 1st seizures and CsA withdrawal
22/04 1.34 241.3 179.63
29/04 1.04 179.8 172.09
02/05 1.04 195 186.64
13/05 1.04 72 68.91
18/05 1.19 40.4 33.83
20/05 1.19 118.1 98.91
2nd seizures and CsA withdrawal
Table 1: Changes of doses, trough concentrations (C0) and bioavailability (C0/ dose) of CsA in time
`