Figure 7: NF-κB and PKC were involved in the regulation of DMT1 in PC12 cells treated with Glu. A shows the expression of DMT1 (+IRE) and DMT1 (-IRE) after PC12 cells were pre-incubated with 5 μM Bay 11-7082 (an NF-κB inhibitor) for 2 h, and then incubated with 100 μM Glu for 12 h (the second column from the left), or then they were continued incubating with 100 μM Glu for another 12 h (the third lane from the left). B PKC activator (PMA) and inhibitor (CH) obviously altered DMT1 (+IRE) expression in PC12 cells (n=6).