Overall Survival Progression-Free-Survival
Variables      HR          95%CI           P-value      HR          95%CI        P-value
Age > 60 years    1.020   1.002-1.032     <0.03    1.013    1.001-1.127      0.06
Age-R > 60 years    1.291   0.775-1.531       0.2    1.010    0.998-1.024      0.09
LDH    1.994   1.501-3.451     <0.0001    1.786    1.560-2.264    <0.0005
LDH-R    2.461   1.711-2.910     <0.0001    1.996    1.501-2.183    <0.0001
Extra-nodal sites > 1    1.027   0.988-1.433       0.1    1.416    0.866-2.391      0.2
Extra nodal sites-R >1    1.981 1.176-2.590 <0.004   1.951 1.325-2.441 <0.006
PS > 1    1.644   0.943-2.313       0.3    1.888    0.987-2.231      0.1
PS-R > 1    2.280   1.438-2.742     <0.0001    2.111    1.473-2.735    <0.002
Stage III/IV    1.207   0.828-1.935       0.3    1.230    0.930-1.813      0.3
Stage-R III/IV    2.067  1.819-2.483      <0.0001    1.997    1.501-2.741   <0.0001
IPI ≥ 2    1.748   1.298-2.280     <0.002    1.810    1.552-2.030    <0.0005
IPI-R > 2    2.618   2.382-3.091     <0.0001    2.258    1.942-2.407    <0.0001
CR prior to transplant    0.119-0.644 <0.0003    0.449    0.223-0.631    <0.0001
ALC-15 (continuous variable)    0.155   0.081-0.282     <0.0001    0.209    0.116-0.360    <0.0001
ALC -15≥ 500 cells/µl    0.252   0.196-0.498     <0.0001    0.288   0.221-0.448     <0.0001
AMC-15 (continuous variable)    2.001   1.489-2.646     <0.0001    2.059   1.541-2.694     <0.0001
AMC-15 ≥ 600 cell/µl   1.261    1.101-2.383     <0.0001    1.315   1.191-2.400     <0.0001
ALC/AMC-15 ratio (continuous variable)   0.100    0.073-0.400     <0.0001    0.117   0.053-0.292     <0.0001
ALC/AMC-15 ratio ≥ 1   0.376    0.273-0.506      <0.0001    0.412  0.317-0.548      <0.0001
ANC-15   0.846    0.735-0.960       <0.009    0.873  0.771-0.978      <0.02
Plts-15   0.991    0.986-0.997       <0.0002    0.993  0.987-0.997      <0.0006
Pre-transplant Rituximab (yes)   0.501    0.170-0.812      <0.0001    0.560  0.259-0.786      <0.0001
Abbreviations: Age-R = age at relapse; Extranodal sites-R = extranodal sites at relapse; LDH = lactate dehydrogenase; LDH-R = lactate dehydrogenase at relapse; PS = performance status; PS-R = performance status at relapse; stage-r = stage at relapse; IPI = International Prognostic Index; IPI-R = International Prognostic Index at relapse; CR = complete remission; PR = partial response; ALC = absolute lymphocyte count; ANC-15 = absolute neutrophil count at day 15; AMC = absolute monocyte count; and plts-15 = platelets at day 15
Table 3: Univariate analysis for Overall Survival and Progression-Free Survival.