(A) Hierarchal clustering of differentially expressed miRNAs in cardiac-induced hESCs by NAM, compared with pluripotent hESCs and neural-induced hESCs by RA. Statistically significant p values and clustering analysis were provided by LC Sciences as part of miRNA microarray service.
(B) A group of cardiac-driving miRNAs displayed an expression pattern of up-regulation upon cardiac induction and down-regulation upon neural induction.
(C) A group of cardiac-driving miRNAs had an expression pattern of up-regulation upon cardiac induction but was not significantly affected upon neural induction.
