Figure 2: Immunosuppressive activity of donor and patient MSCs in mixed lymphocyte culture. MNC – peripheral blood mononuclear cells. The data are presented as M ± SE of suppressor activity index (the ratio of T-cell proliferation level in the presence of MSCs to that without MSCs) of donor MSCs (n=7), lymphoma patient MSCs (n=12), AL patient MSCs (n=5), AA patient MSCs (n=9). MSC suppressor activity was tested in mixed lymphocyte culture (MLC; each MSC population was tested in three MLC). * - P <0.05, ** - p <0.01 - significant difference in comparison with bone-marrow MSCs from healthy donors (Mann-Whitney test).