Figure 5: The effect of FGFb on immunosuppressive activity of donor and patient MSCs in mixed lymphocyte culture. MNC – peripheral blood mononuclear cells. The data are presented as M ± SE of suppressor activity index (the ratio of T-cell proliferation level in the presence of MSCs to that without MSCs) of donor MSCs (n=7), lymphoma patient MSCs (n=10). MSC suppressor activity was tested in mixed lymphocyte culture (MLC; each MSC population was tested in three MLC). Significance of differences between FGFb(-) and FGFb(+) groups was calculated with Wilcoxon test for related pairs.