Figure 7: Insulin (green), glucagon (red) and SOX17 (blue) expression during the third trimester of human fetal development (24wpc-birth(38wpc)) as demonstrated by samples 29 and 38 wpc, as well as 10 wpn, and adult. In the third trimester, SOX17 expressing cells are initially associated with glucagon expressing cells at 29 wpc, however as the insulin and glucagon expressing cells become intermixed by 37 wpc and post natally, the SOX17 expressing cells also are intermixed with other cell types within the islets. SOX17 is not co-expressed in insulin or glucagon expressing cells in the third trimester or post natally. Areas surrounded by a box are shown at higher magnification (inset). Scale bars are 50 and 10 μM respectively.