Figure 1: Methylation cycle and inhibitors (dotted line). Abbreviations: MS: methionine synthase, SAHH: Sadenosylhomocysteine Hydrolase, MAT: methionine adenosyltransferase, THF: tetrahydrofolate, SAM: S-adenosylmethionine, SAH: S-adenosylhomocysteine, methyl acceptor can indicate DNA, RNA, protein or lipid. MT: methyltransferase. Adox: periodate oxidized adenosine as methylation inhibitor for SAHH.