Light microscopy Without GVHD With GVHD P Moderate Inflammatory infiltrate 2(25%) 5(45%) 0.669 Intraepithelial lymphocytes (no./hpf) 12 7.2 0.098 Apoptotic body (no./hpf) 5.3 6.6 0.482 Eosinophils (no./hpf) 4.2 14.4 0.641 Glandular density (no./hpf) 11 6.7 0.126 Moderate/severe edema 1(12%) 6(54%) 0.16 Fibrosis 0 3(27%) 0.332 Basal membrane (mm) 0.048 0.032 0.858

Table 2: Analysis of the sinonasal optical microscopy of patients transplanted with hematopoietic stem cells, with and without graft versus host disease (GVHD) epithelium. Fisher’s exact test and Wilcoxon analysis with P value<0.005. (No./ hpf=number per field of greatest increase, mm=millimeters).