Wound type Cell type Delivery system Outcome Reference
Chronic wounds (n=3) BM-MNC BM-MSC BM-MNC, injected into wound BM-MSC, topical application All wounds healed. Increased inflammatory response and angiogenesis Badivas and Falanga [61]
Acute surgical wounds (n=4) and Chronic lower limb ischemia (n=6) BM-MSC Topical delivery using fibrin spray Reduction in chronic wound size. BM-MSC engraftment in  blood vessels Falanga et al. [66]
Intractable dermatopathies (n=20) BM-MSC BM-MSCs on collagen Sponges used as wound dressings Wound healed in 18 of 20 patients Yoshikawa et al. [67]
Nonhealing ulcer or Lower extremities (n=24) BM-MSC Intramuscular injection and topical application Improvement in pain-free walking. Ulcer size decreased by 72% in BM-MSC treated group Dash et al. [62]
Diabetic critical limb ischemia with foot ulcers (n=41) BM-MNC BM-MSC Intramuscular injection Improvement in pain-free walking time and fastest rate of healing in  treated group Lu et al. [63]
Pressure ulcers (n=22) BM-MNC Injection into the  edges of the wound Wound healed in 19 of 22 patients Sarasua et al. [64]
Critical limb ischemia ASC Multiple intramuscular injection Clinical improvement of 66.7% Lee et al. [74]
Effects of radiation ASC Repeated transplants, irradiated areas Significant clinical improvements.  Most patients Riggoti et al. [77]
Rectovaginal fistula ASC, heterologous First case   exhibited no rejection or adverse events, but the fistula remained  open Garcia-Olmo et al. [75]
Perianal fistula ASC Fibrin glue Effective at inducing healing Garcia-Olmo et al. [76]
Table 1: Summary of the use of cell therapy in wound healing.