Figure 2: Teratoma formation from human iPSC in NOD/SCID mice. Teratoma staining in NOD/SCID mice demonstrated formation of all three germ layers. Endodermal structures included (A) glands and (B) ducts. Sections of the mesoderm revealed (C) cartilage, (D) ossifying cartilage, and (E) blood vessel formation. The ectoderm contained (F) pigmented cells in addition to (G) neuronal rosette formation (shown by black arrows). (Magnification 200X).