| Visual acuity (Log Mar) | Functional epithelium | Functional signs | ||||||||||||||
| Patient | Sex | Age | Initial disease | Years from the event | Baseline | one year | Long term | Baseline | one year | Long term | Baseline | one year | Long term | Previous surgeries | Surgeries post CAOMECS | |
| 001 | M | 48 | Chemical burn | 26 | 1.9 | 1.7 | 1.9 | No | Yes | Yes | 0/2/1 | 0/0/0 | 0/0/0 | 4 PK | DALK. PK. AM | |
| 003 | W | 69 | Rosacea keratitis | 27 | 2.30 | 1.70 | 1.90 | No | Yes | No | 1/2/1 | 1/0/0 | 1/0/1 | 0 | DALK | |
| 006 | M | 70 | Corneal burn | 36 | 1.00 | 1.70 | 0.80 | No | Yes | Yes | 1/1/1 | 1/0/0 | 0/0/0 | 0 | PK. PK+EEC | |
| 007 | M | 54 | Corneal burn | 1.70 | 1.90 | 0.70 | No | Yes | Yes | 2/2/1 | 1/0/0 | 0/0/0 | PK | PK | ||
| 009 | M | 41 | Lyell syndrome | 20 | 1.70 | 0.70 | 0.40 | No | Yes | Yes | 1/2/0 | 0/0/0 | 0/0/0 | 3 PK. CS | PK | |
| 010 | M | 80 | Rosacea keratitis | 43 | 2.30 | 1.70 | 2.10 | No | Yes | Yes | 1/1/0 | 0/0/0 | 0/0/0 | 0 | DALK | |
| 011 | M | 59 | Corneal Burn | 5 | 1.70 | 1.30 | 0.70 | No | Yes | Yes | 2/2/0 | 0/0/0 | 0/0/0 | 3 PK. CS | PK | |
| 018 | M | 60 | Congenital aniridia | 61 | 0.80 | 1.70 | 1.90 | No | No | No | 2/1/1 | 1/0/0 | 1/0/0 | CS | DALK | |
| 020 | M | 69 | Groenow dystrophy | 18 | 2.30 | 2.00 | 2.50 | No | Yes | No | 1/1/0 | 0/0/0 | 0/0/0 | 5 PK | PK | |
| Visual acuity (Log Mar) | Functional epithelium | Functional signs | |||||||||||||
| Patient | Sex | Age | Initial disease | Years from the event | Baseline | 1 year | Long term | Baseline | one year | Long term | Baseline | one year | Long term | Previous surgeries | Surgeries post CAOMECS |
| 002 | W | 38 | Neuroparalytic Keratitis | 20 | 1.00 | 0.50 | 0.40 | No | Yes | Yes | 1/2/1 | 0/0/0 | 0/0/0 | 0 | 0 |
| 004 | M | 40 | Corneal burn | 1 | 1.60 | 1.00 | 1.30 | No | No | Yes | 2/1/0 | 2/0/0 | 2/0/0 | AM | 0 |
| 008 | M | 61 | Severe trachoma | 60 | 1.90 | 1.60 | 1.60 | No | Yes | Yes | 2/2/1 | 1/0/0 | 1/0/0 | CS. 2 PK | PK |
| 012 | M | 38 | Corneal burn | 10 | 1.00 | 0.70 | NA | No | Yes | Yes | 2/0/1 | 0/1/0 | 0/1/0 | DALK. AM | 0 |
| 014 | M | 53 | Corneal burn | 5 | 2.30 | 2.30 | 2.10 | No | No | No | 1/1/1 | 0/1/0 | 0/0/0 | AM. PS | lamellar keratotomy without cornea graft+AM+CS |
| 015 | W | 51 | Contact lens hypoxia/congenital cataract | 1.00 | 0.60 | NA | No | Yes | Yes | 2/2/1 | 0/0/0 | 0/0/0 | 0 | 0 | |
| 016 | W | 71 | Lyell syndrome | 9 | 2.30 | 2.00 | 2.30 | No | Yes | Yes | 3/1/1 | 1/0/0 | 0/0/0 | AM. PK | 0 |
| 017 | M | 50 | Lyell syndrome | 5 | 1.30 | 1.00 | 0.60 | No | No | No | 0/3/0 | 0/0/0 | 0/0/0 | AM | 0 |
| 019 | W | 25 | corneal opacity due to cystinosis | 23 | 2.30 | 2.30 | 2.30 | No | No | No | 2/1/2 | 0/0/0 | 0/0/0 | 0 | 0 |
| 021 | M | 46 | Keratitis/Hepatitis C | 14 | 1.00 | 0.70 | 0.50 | No | Yes | Yes | 1/0/1 | 0/1/0 | 0/1/0 | 0 | 0 |
| 022 | W | 38 | Neuroparalytic Keratitis | 20 | 0.50 | 0.40 | 0.40 | No | Yes | Yes | 2/2/0 | 0/0/0 | 0/0/0 | DALK | 0 |
| 023 | W | 33 | Congenital aniridia | 33 | 1.90 | 1.90 | 1.70 | No | Yes | Yes | 2/1/1 | 0/0/0 | 0/0/0 | 0 | Trabeculectomy |
| 025 | W | 54 | Rosacea keratitis | 24 | 2.30 | 2.10 | 2.30 | No | No | No | 2/1/1 | 2/1/0 | 0/0/0 | 0 | simultaneous PK+CS+CAOMECS |
| 026 | M | 55 | Acid corneal burn | 1 | 2.30 | 1.90 | 1.90 | No | No | No | 2/0/1 | 2/0/1 | 2/0/1 | 0 | 0 |
Table 2.1 Results of OCS group including patients who received a post-CAOMECS donor graft;
Table 2.2 Results of CCS group including patients whose stroma was healthy.
The results are presented respectively for Photophobia/Dryness/Pain as 0-1-2-3 /0-1-2-3 /0-1-2-3
Improvement at long term n=16
Failure of clinical trial (1 year) n=9Woman (W) Man (M) Perforating Keratoplasty (PK) Deep Anterior Lamellar Keratoplasty (DALK) Amniotic Membrane Transplantation (AM), Cataract Surgery (CS), Palpebral Surgery (PS)
