Figure 3: Representative MR images with T2-sagittal before intervention and before sacrifice with corresponding color coded ADC maps. Control designates normal intervertebral disc; Degen– disc with induced IDD, no local treatment, while Stem Cell designates local stem cell therapy. In the degenerative disc the white water filled nucleus pulposus has disappeared compared to a normal disc where the NP is bright and with normal disc height. The Modic Type 2 changes seen in adjacent endplates to the degenerative disc remain unchanged. In the level receiving stem cell transplantation the NP increase a litte in size and brightness.