Molecular and Cellular Functions p-value # Genes Growth, Proliferation 8.47E-05–1.81E-02 172     Cell Death 4.76E-06–2.04E-02 253     Small Molecule Biochemistry 1.89E-05–1.89E-02 104     Amino Acid Metabolism 1.89E-05–1.43E-02 17     Lipid Metabolism 2.72E-05–1.89E-02 79 Diseases         Cancer 6.52E-14–2.22E-02 448     Reproductive System Disease 3.10E-05–1.86E-02 151     Gastrointestinal Disease 1.47E-06–2.10E-02 126 Top Canonical Pathways      NRF2-mediated oxidative stress response 1.65E-06 23     Pyrimidine Metabolism 5.35E-03       Interferon Signaling 6.18E-03       Glutathione Metabolism 5.02E-03

List of the most significantly regulated pathways modulated by NO in MSC. The molecular and cellular functions of the annotated pathways are listed in the left column, the levels of significances (i.e., p-value) for changes in NO-dependent gene regulation in the respective pathways in the middle, and numbers of factors or genes regulated by NO in the right column (1.5 mM SNP, 24 hrs)

Table 1: Significant NO-regulated pathways in human MSC: a brief summary of microarray data.