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Figure 1: Evaluated parameters in seizures induced by MES. Analysis of tonic duration indicated a reduction in day 3 (A), day 4 (B) and day 5 (C) of MES stimulation for the MCAT-MES group (n=12) when compared to the CTRL-MES group (n=12); D) The duration of post-ictal period also decreased in MCAT-MES group; E) Clonic seizures after MES stimulation comparing CTRL-MES and MCAT-MES groups indicated an increase in MCAT-MES; and F) percentage of mortality rate shows considerable reduction in of MCAT-MES group compared to CTRL-MES group (*p< 0.05, Student t test; in F Chi-square). From A to E, data represented by mean + S.E.P. |