Figure 5: In vivo teratoma formation of piPS/hrGFP+ cells. (A) Teratomas formation tracked by In Vivo Imaging System. (B) Hematoxylin and eosin staining of teratomas derived from piPS/hrGFP+ cells showed multiple tissues, including neural tissues, keratin pearls, skeletal muscle, smooth muscle, cartilage, adipose tissues, and glandular structures. (C) Immunohistochemical staining confirmed that piPS/hrGFP+ cells differentiated into neural tissues, keratin pearl, and cardiac tissues in teratomas.