Figure 6: Multilineage differentiation of lung-derived MSCs. Adipogenic differentiation. The adipogenic differentiation was confirmed by the detection of small intracellular lipid droplets (oil red O staining). Yet, a final differentiation into mature adipocytes containing large, fused lipid vacuoles was not achieved. Results are presented as mean and SEM. On the ordinate axis – number of cells with intracellular lipid droplets, on the abscissa - examined groups: mice with intratracheal administration of NaCl 0.9%, mice with intratracheal administration of bleomycin, mice with intratracheal administration of bleomycin and spiperone-treated. Percentage of cells with lipophilic inclusions from the total cultured cells in the experimental group was 4.00 ± 0.39%, the samples of the control group - 11.00 ± 2.32% (n = 8, p <0.001), in the samples of bleomycin control - 10.00 ± 1.85% (n = 8, p<0.001).