| Groups |
Lin-Sca-1+c-kit+CD34- - cells |
Lin-Sca-1+c-kit+CD34+ - cells |
Lin-Sca-1+c-kit+ - cells |
| Lung |
| Mice received intratrachealNaCl 0.9% |
0.07 ± 0.005 |
0.018 ± 0.001 |
0.088 ± 0.007 |
| Mice with fibrosis NaCl 0.9% treated |
0.12 ± 0.01* |
0.06 ± 0.005* |
0.18 ± 0.01* |
| Mice with fibrosis spiperone treated |
0.097 ± 0.008* |
0.03 ± 0.002* & |
0.128 ± 0.011* & |
| Bone marrow |
| Intact control |
0.39 ± 0.03 |
0.071 ± 0.006 |
0.46 ± 0.04 |
| Mice with fibrosis NaCl 0.9% treated |
0.35 ± 0.03 |
0.051 ± 0.005* |
0.4 ± 0.03 |
| Mice with fibrosis spiperone treated |
0.43 ± 0.04 |
0.11 ± 0.01* & |
0.54 ± 0.05 & |
Membrane receptor’s expression of murine HSCs from bone marrow or lung were assayed according to the protocol for BD Mouse Hematopoietic Stem and Progenitor Cell Isolation Kit (BD Biosciences, US). Data represent mean of 3 independent experiments. Results are presented as mean and SEM. * P<0.05 - compared to the mice received intratracheal NaCl 0.9%; & P<0.05 - compared to the mice received intratracheal bleomycin and NaCl 0.9% treated.