Figure 5: hOXR1-MSCs transplantation suppressed anti-GBM induced nephritis in 129/svj mice. (A) BUN levels in hOXR1-MSCs and pCDH-MSCs treated anti-GBM challenged 129/svj mice. (B) Twenty-four hour proteinuria levels in hOXR1-MSCs and pCDH-MSCs treated anti-GBM challenged 129/svj mice. (C-D) Representative images of PAS stained renal sections from pCDH-MSCs injected or hOXR1-MSCs injected 129/svj mice with anti-GBM nephritis. (C) Exemplified is some of the typical light microscopic features in anti-GBM induced nephritis in 129/svj mice with pCDH-MSCs treatment. (D) hOXR1-MSCs injected mice showed very mild renal histological changes. (E) Renal pathology score of anti-GBM challenged 129/svj mice treated with pCDH-MSCs, or hOXR1-MSCs. (Original magnification 400X, scale bars=50 μm). Each group had 5 mice.